China (Mainland)
Imatinib mesylate CAS NO.220127-57-1
- FOB Price: USD: 830.00-835.00 /Kilogram Get Latest Price
- Min.Order: 1 Gram
- Payment Terms: L/C,D/A,D/P,T/T,Other
- Available Specifications:
A(1-50)KilogramA(50-100)Kilogram
- Product Details
Keywords
- Imatinib mesylate
- Imatinib methanesulfonate salt
- mesylate
Quick Details
- ProName: Imatinib mesylate
- CasNo: 220127-57-1
- Molecular Formula: C29H31N7O?CH3SO3H
- Appearance: Crystalline powder
- Application: It is a selective tyrosine kinase inhi...
- DeliveryTime: Min 3 Days
- PackAge: Drum/Bag
- Port: Chengdu Port
- ProductionCapacity: 1 Metric Ton/Day
- Purity: 99.0%
- Storage: Store at 4° C
- Transportation: By Air/Sea
- LimitNum: 1 Gram
- Melting Point: 214-224 °C
- Boiling Point: 54.9 °C at 760 mmHg (Predicted)
- Refractive Index: n20D 1.67 (Predicted)
- IC50: PDGFR: IC50 = 0.1 μM; c-Kit: IC50 = 0....
Superiority
Mature technology, high purity, Deeply Prided By Customers
Details
Imatinib mesylate is a small molecule that inhibits the c-Abl protein-tyrosine kinase, a kinase specifically important fproliferation ofonic myelogenous leukemia (CML). A translocation event betweenomosomes 9 22 generates the Philadelphiaomosome, which then produces the Bcr-Abl fusion protein with aberrant kinase activity that promotes rapid cell proliferation. Imatinib binds up this crucial kinase, halting CML related growth. Imatinib mesylate has further been displayed to inhibit PDGFR tyrosine kinases associated with c-Kit.
